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Why It's Important: Among other things, the TREM2 protein is involved with phagocytosis by microglia.
Relating a variant in this gene/protein to AD strongly supports the involvement of microglia and the immune system in the pathogenesis of this important disease and also adds another factor to genetic risk for AD.
The daily barrage of “groundbreaking” news in neurology research makes it challenging for clinicians to decipher what is truly important for their practice.
We asked members of our editorial advisory board — all leaders in the field — to help separate the “wheat from the chaff,” so to speak, in highlighting the most important advances, policies, and developments this year.
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